The ultimate craft beer vacation, the Lebrewski Cruise, just wrapped up several days out at sea. Featuring a number of exceptional refreshments from breweries like Boulder Beer Company, Cigar City, Lagunitas Brewing, Left Hand and Stone Brewing, and musical performances from O.A.R., Kyle Hollingsworth of the String Cheese Incident as well as SCI bandmates Michael Kang and Jason Hann and more, the Lebrewski Cruise is certainly a one of a kind experience.Having put three members of SCI on the cruise, it didn’t take a brewmaster to figure out there would be significant collaborations along the way. Cue Jason Hann’s Rhythmatronix. Featuring Hann, Michael Kang, Fareed Haque (Sting, Joe Zawinul, Garaj Mahal), Raul Pineda (Chucho Valdez, Sintesis), Oteil Burbridge (Dead & Company, Allman Brothers Band), and Todd Stoops (RAQ), the Rhythmatronix delighted onlookers to a grooving, jazz inspired, improvisational-laced set.You can watch Jason Hann’s Rythmatronix’s entire set from the Lebrewski Cruise below:Setlist: Jason Hann’s Rythmatronix at the Spinnaker Lounge, Lebrewski Cruise – 3/2/16Set: Opus Pocus, Havona, Palladium, Manga, Raul Drum Solo, Gibraltar
The contest for this year’s Tiny Desk Contest is now closed, as NPR has picked the winning songwriter/performer from over 6,000 entries to star in their own episode of the popular online performance series. While bands and artists from across the country (including Pigeons Playing Ping Pong and Midnight North) all submitted their entries to win the popular video contest, NPR announced on Thursday that Quinn Christopherson has been chosen and crowned this year’s winner.Related: Weezer Performs Career-Spanning Set For NPR Tiny Desk ConcertChristopherson and his bandmate Nick Carpenter chose to go with their original tune, “Erase Me”, for their impressive entry. The young songwriter hails from Anchorage, Alaska, but the surrounding northern wilderness didn’t stop him from putting together a warm and captivating indie-folk ballad to take home this year’s highly-coveted industry contest.The winning video sees (and hears) Christopherson and Carpenter taking their place in a spacious room which is uniquely decorated with a flannel chair, a few amplifiers, and a large painting which acts as the official backdrop for the performance. Throughout the nearly six-minute video, Christopherson–who describes himself as a transgender and associated with Athabaskan and Inupiaq indigenous cultures–can be heard belting out inspiring lyrics such as, “I’ve got a voice now/I got power/But I can’t stand it” and “Nobody interrupts me/And nobody second-guesses my opinions.”Watch the winning entry for this year’s Tiny Desk Contest below.Quinn Christopherson – “Erase Me” [Video: Quinn Christopherson]Christopherson now finds himself in impressive company, as the annual Tiny Desk Contest has spent the last two years introducing music fans to Tank and The Bangas in 2017 and Naia Izumi in 2018. Christopherson’s next stop will be the NPR offices in Washington, D.C., where he’ll get to star in his own Tiny Desk performance.[H/T NPR]
The American Philosophical Society, the oldest learned society in the United States, recently elected four new members from Harvard into this year’s class of scholars.The society, founded in 1743 by Benjamin Franklin for the purpose of “promoting useful knowledge,” honors and engages distinguished scientists, humanists, social scientists, and leaders in civic and cultural affairs through elected membership and opportunities for interdisciplinary intellectual fellowship, particularly in the semiannual meetings in Philadelphia. Since 1900, more than 240 members have received the Nobel Prize.This year’s elected members from Harvard follow:Ben Heineman, senior fellow, Belfer Center for Science and International Affairs; distinguished senior fellow, Harvard Law SchoolSarah Blaffer Hrdy, associate of the Peabody Museum of Archaeology and EthnologyRobert Sampson, Henry Ford II Professor of the Social SciencesPatrick Thaddeus, Robert Wheeler Willson Professor of Applied Astronomy
Harvard University will invest new resources immediately to expand and strengthen its Office of Sexual Assault Prevention and Response, President Drew Faust announced today. The increase in resources was among a series of immediate actions recommended by the Sexual Assault Task Force, which is led by former Harvard Provost Steven E. Hyman.In addition to the investment in that office, recommendations include creation of a website that aggregates and clearly highlights the broad array of current prevention and response resources in one location; resources on which the Schools can draw as they devise training and orientation programs for the fall; and a campus survey to assess the incidence, circumstances, and perceptions of sexual assault and other forms of sexual harassment at Harvard.Faust accepted the recommendations and said that the University “will move at once to implement your four recommendations for immediate action.”The recommendations were developed after the first two task force meetings and were included in a May 13 letter from Hyman to Faust, who commissioned the group earlier this spring.“Reflecting the urgency of the issue, we chose to begin our work immediately,” wrote Hyman, former director of the National Institute for Mental Health. “During the summer, we will gather data on effective practices developed by other universities and by the military, and will also review relevant academic literature. In addition, we plan to develop survey instruments attuned to the Harvard community. A critical activity that will begin as soon as students and faculty return in the fall will be a process of broad outreach to members of the Harvard community to gather input.“While we have much work in front of us in the next months, we have determined that there are several steps that can be taken now,” he wrote, strongly recommending immediate new support for office, the website, the fall programming, and the proposed campus survey.Hyman emphasized that the new resources are being made necessary by the increased national focus on sexual misconduct on college campuses.“With renewed attention to sexual assaults, the call for services has increased and will likely continue to do so,” he wrote.In accepting the recommendations, Faust thanked the task force for its focus on near-term improvements and said the University must “do better” on issues related to sexual assault.“As I noted when the task force was constituted, Harvard will meet our legal obligations, but they alone should not bound our response to this behavior,” wrote Faust. “We can, and indeed we must, do better.“We have the responsibility to think in new ways about the best means of preventing sexual assault and ensuring that we are effectively responding to those who have experienced it.”Hyman was instrumental in creating the office in 2003, a reform that significantly bolstered Harvard’s ability to respond to incidents of misconduct and to support those who had experienced sexual harassment, including assault. The new director of the office, Alicia Oeser, is a task force participant.For more than a year, the University has worked to respond to the rapidly evolving legal landscape and to the needs of students, faculty, and staff. Last spring, the first University Title IX officer, Mia Karvonides, was hired. She convened a working group last May to review existing, School-based Title IX policies and procedures. That group produced the first University-wide Title IX policy, which has been submitted for review to the U.S. Department of Education’s Office of Civil Rights.
Eric Nelson, the Robert M. Beren Professor of Government at Harvard, has been named a finalist for the 2015 George Washington Book Prize. One of the nation’s largest and most prestigious literary awards, the prize recognizes the best new books on early American history. Now in its 11th year, the award recognizes works that not only shed new light on the nation’s founding era, but also have the potential to advance broad public understanding of American history.This year’s honorees spark new thinking on the American Revolution: its causes and principles, the meaning of liberty and freedom in the young democracy, and the impact of the revolution that reverberated throughout the 18th-century Atlantic world. Nelson’s “The Royalist Revolution: Monarchy and the American Founding” (Harvard University Press) turns upside-down the conventional image of the war as a rebellion against a tyrannical king.Nelson is also the author of “The Hebrew Republic: Jewish Sources and the Transformation of European Political Thought” (2010) and “The Greek Tradition in Republican Thought” (2004).The award is sponsored by the Gilder Lehrman Institute of American History, George Washington’s Mount Vernon, and Washington College. The winner of the $50,000 prize will be announced at a black-tie gala on May 20 at Mount Vernon.
The dietary factor Flight attendants have higher rates of breast, uterine, other cancers Drug resistance is the leading cause of death in women with estrogen-receptor-positive breast cancer, the most common form of the disease. Now, researchers have identified an ordinary dietary element that may increase the chances of a breast cancer becoming drug-resistant.The connection of the amino acid leucine — found in foods such as beef, pork, chicken, fish, dairy products, and beans — to drug resistance raises hopes that a relatively simple intervention, like a shift to a low-leucine diet, can reduce the incidence of drug resistance, which is responsible for a large portion of the roughly 40,000 breast cancer deaths every year.The work also raises the possibility that a drug could be developed to mirror the effects of that dietary restriction, by blocking cells’ ability to take in leucine from the surrounding environment.Senthil Muthuswamy, an associate professor of medicine at Harvard Medical School and director of the cell biology program at the Cancer Center at Beth Israel Deaconess Medical Center, said scientists in his lab have already begun experiments with mice to see whether dietary changes can make a difference in the disease’s course. They’re also exploring whether an experimental drug already in clinical trials for another purpose can block tumor cells’ ability to take up leucine.“A lot of women are dying because of this condition,” Muthuswamy said. “So if you can have any impact on that cohort, whether it is through a drug or simple dietary manipulations combined with some other treatment, that would be huge. I would be ecstatic.”The research was led by Muthuswamy and funded by a grant from the National Institutes of Health and the Breast Cancer Research Foundation. It was conducted by team that included research fellow Yasuhiro Saito, first author of a paper published recently in the journal Nature, and colleagues from Beth Israel, the Dana-Farber Cancer Institute, Keio University in Japan, the Princess Margaret Cancer Centre in Toronto, and the University of Toronto. The Daily Gazette Sign up for daily emails to get the latest Harvard news. New weapon against breast cancer Molecular marker in healthy tissue can predict a woman’s risk of getting the disease, research says Related Could a popular food ingredient raise the risk for diabetes and obesity? Race bias seen in breast-cancer screening Current guidelines can delay diagnosis in nonwhite women, analysis says The potential interventions would apply to estrogen-receptor-positive, or ER+, breast cancer, which accounts for about 70 percent of the approximately 260,000 annual cases in the U.S. ER+ breast cancer cells are nurtured by the hormone, so estrogen-blocking drugs such as tamoxifen have been developed to stop their growth and spread.But, Muthuswamy said, resistance to tamoxifen and other estrogen-blocking drugs is a major cause of recurrence and metastases. Once resistance can keep any of the available estrogen-blocking drugs from working, death usually follows in two to three years.“It’s really a horrible state at that point,” Muthuswamy said. “I was driven by that and trying to see if this would provide any insight into endocrine resistance, because I’m very interested in trying to help those patients.”Muthuswamy and his team found that tamoxifen-resistant breast cancer counters the drug’s effects by increasing its intake of leucine, an amino acid that the body normally uses to make proteins and that must be consumed in food. In experiments on mice seeded with tamoxifen-resistant breast cancer cells, researchers found that blocking leucine from entering the cells resulted in the resistant tumors shrinking.The work grew out of a general investigation of how ER+ breast cancer cells respond to a stressful environment. Researchers first found that cells increased their use of leucine, and as the scientists explored the relationship between leucine and breast cancer cells, they found that a molecule called SLC7A5 on the cell surface plays a key role by transporting leucine from the surrounding environment into the cells.They also found that when leucine was scarce in the environment, cells moved more SLC7A5 to the cell surface, and that tamoxifen-resistant cells had more SLC7A5 on their surface than nonresistant cells did. Cells with extra SLC7A5 on their surface were able to grow and divide even in leucine-poor environments.In addition to the follow-up clinical research already begun, Muthuswamy said his lab is investigating basic science questions, such as the mechanism by which leucine nourishes cancer cells and how the transporter molecule SLC7A5 moves from within the cell to the cell surface.Muthuswamy said he is excited by the findings and by the prospect that positive results in the next phase of investigation could result in the rapid transition to the clinic of a new tool to fight ER+ breast cancer. Oncologists, he said, are routinely asked by patients whether a particular diet will help, and perhaps they will soon be able to give a more hopeful answer.“Invariably, almost all physicians tell them, ‘Just eat a healthy diet,’” Muthuswamy said. “Managing endocrine resistance is one of the biggest clinical problems in breast cancer.” U.S.-focused analysis suggests need for stronger protection against radiation, researchers say
Sign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York Nassau County police Homicide Squad detectives are investigating the death of a 63-year-old Long Beach woman who was struck by a car at an intersection in her hometown Thursday morning, police said.The victim was identified by police as Deborah Batus, who was pushing a baby stroller filled with garbage when she was struck at the intersection of East Park Avenue and Pacific Boulevard at 6:32 a.m. There was no child in the stroller.Batus was transported to Long Beach Hospital, where she was pronounced dead at 7:05 a.m.Police did not reveal information about the driver involved in the crash.
As the goals of the new Law on Maritime Property and Seaports, which was presented today at the session of the Tourist Business Council of the Croatian Chamber of Commerce by State Secretary in the Ministry of the Sea, Transport and Infrastructure Maja Markovčić Kostelac, the need for maritime property as a specific concession object was clarified. which meet investors-concessionaires and potential concessionaires in practice and respect for the maritime domain as an ecologically and touristically important element of Croatia’s identity in Europe and the world. “We have high expectations from this law, as well as from the Law on Tourist Land, as the flywheel of a new investment cycle in tourism. Currently, the law in some segments does not take into account the situation on the ground, and there is a legal mess regarding concessions because it is not harmonized with the Law on Concessions. Another problem we face is of a land-book nature. Based on the views received so far by the members of the Croatian Chamber of Commerce on the draft law, there are opposing views, but we hope that, guided by the principles of economic efficiency and sustainability, we will reach a compromise., “Said the Vice President of the Croatian Chamber of Commerce for Agriculture and Tourism Dragan Kovačević, emphasizing that the Croatian Chamber of Commerce will submit the collected opinions to the Ministry and that from now on the sessions of the Tourist Business Council will be thematically conceived with regard to current segments of the tourism sector.State Secretary Maja Markovčić Kostelac pointed out the Law on Maritime Property and Seaports as the most important for economic development and preservation of the sea and coast as the most important resources, along with the Maritime Code and the Law on Harbor Master’s Offices as a remnant of the Ministry’s legislative framework. announced the recent opening of a public hearing on the proposal.Hotel & Marina Nautica, Novigrad / Photo: Photo: Ziga Intihar”With the proposal of the Law, we want to increase the competitiveness of the economy, reduce administrative barriers and achieve a balance in all this, given the need for simultaneous protection of resources. The zero point in this is the determination of the border of the maritime domain and the acceleration of the process of registration of the maritime domain. The new Act sets a three-year deadline for determining the maritime domain boundary for the entire coast. Competence for determining the border is transferred to the units of regional self-government, and an urgent procedure for registration is prescribed, “Said Markovčić Kostelac.Markovčić Kostelac also touched on the issue of illegally constructed buildings on the maritime domain, which the goal is to legalize if they are not contrary to the spatial plan of a certain area. She also pointed out the maritime inspection as one of the weak points, whereby the new law would expand the powers of the existing inspection, and give new ones to communal and port wardens.For the economic use of maritime property, two institutes are established, concessions and permits. Markovčić Kostelac pointed out the possibility of introducing only a permanent part of the concession fee for individual concessions, and based on the conducted zoning of the coast, the initial amounts of the concession fee for each individual economic activity and zone will be determined. Revenues from licenses on the maritime domain are divided equally in half With the aim of raising the competitiveness and efficiency of ports open to public traffic, the Port Authority becomes responsible for the direction and traffic of cargo and passengers with the basic goal of economic growth of the port it manages. Investments in the port should be exempted from paying the utility fee by the new Law, and in terms of revenues from the concession fee, the fee for maritime property paid by boat owners for personal needs would be abolished. Revenues from the concession fee would be divided as follows: 35% in favor of the budget of the local self-government unit, 35% in favor of the regional self-government, and 30% in favor of the state budget. Revenues from licenses on maritime domain are divided so that 50% goes to the budget of the local unit, and 50% to the budget of the regional self-government. After the presentation of the bill, during a discussion with representatives of the tourism sector, State Secretary Markovčić Kostelac pointed out the issue of granting concessions for beaches as allocating a large area to one business entity can have a negative effect on the rest of the economy and the whole place.Representatives of the sector, specifically hoteliers and camp owners, pointed out that the beach directly in front of the facility is a key part of their offer and maintaining the desired categorization. As one of the solutions, they proposed the introduction of the right to a certain advantage to the concession, and pointed out the problem of expiration of concessions, where representatives of hoteliers and camps proposed that in upcoming tenders can be valued concessionaires who have previously managed certain maritime assets and invested into him.
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Advertisement Cesc Fabregas singles out Bukayo Saka for special praise in Arsenal’s draw with Man Utd Comment Advertisement Saka celebrates after setting up Aubameyang’s equaliser at Old Trafford (Picture: Getty)The youngster – who scored and assisted twice in the Europa League against Frankfurt – had Arsenal’s best chance of the first half, prompting a fine double save from David de Gea, and could have scored in the second.AdvertisementAdvertisementADVERTISEMENTHe appeared to have the beating of veteran Ashley Young throughout, with his pace threatening constantly, while he assisted Pierre-Emerick Aubameyang’s equaliser – and Fabregas believes his old club might have unearthed a gem.‘Saka is a player. Eighteen years old and showing great maturity,’ he tweeted, also posting a clapping hands emoji.More: FootballRio Ferdinand urges Ole Gunnar Solskjaer to drop Manchester United starChelsea defender Fikayo Tomori reveals why he made U-turn over transfer deadline day moveMikel Arteta rates Thomas Partey’s chances of making his Arsenal debut vs Man CityWhile Fabregas was excited by what he saw from Saka, he seemed decidedly less impressed with the quality on show from both teams in what was a largely uninspiring match lacking in quality.‘Thoughts on the game so far without using a bad word? Try to be creative,’ he added.18y 25d – Bukayo Saka is the youngest player to ever start a @premierleague match between Manchester United and Arsenal. Stage. #MUNARS pic.twitter.com/CAb7fXIYRm— OptaJoe (@OptaJoe) September 30, 2019 The youngster was a real bright spark for the Gunners at Old Trafford on Monday (Picture: AFP)Former Arsenal midfielder Cesc Fabregas was quick to praise the precocious talent of Bukayo Saka in a largely uninspiring performance for the Gunners in their draw with Manchester United.Unai Emery’s side went behind on the stroke of half-time to a ferocious Scott McTominay strike, with the quality of the goal in stark contrast to the sub-par play that had preceded it.Both teams seemed to struggle in the wet and slippery conditions at Old Trafford on Monday night, but the 18-year-old Saka was a rare bright spark for the visitors. Metro Sport ReporterMonday 30 Sep 2019 10:02 pmShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link911Shares Things certainly livened up in the second period, with Aubameyang latching onto a neat pass from Saka and levelling the scores after his effort had initially been ruled out for offside by the linesman – though VAR showed he was clearly onside.The game became more open-ended after Aubameyang’s equaliser, with United pressing to try and find a winner, though the spoils were shared; the result moves Arsenal up to fourth, while United are in 10th place.More: Manchester United FCRio Ferdinand urges Ole Gunnar Solskjaer to drop Manchester United starNew Manchester United signing Facundo Pellistri responds to Edinson Cavani praiseEx-Man Utd coach blasts Ed Woodward for two key transfer errors